nucleocapsid protein (247-363)
Protein Sequence
Sequence Variants
| ID | Name | Remain region | Mutation sites | Ref seq |
|---|---|---|---|---|
| psp03119 | nucleocapsid (N) protein | 1-419 | - | ✓ |
| psp04332 | nucleocapsid protein (247-363) | 247-363 | - | |
| psp00051 | nucleocapsid protein (ΔCTD 248-366) | 1-246, 366-419 | - | |
| psp00341 | nucleocapsid protein d_IDR1 | 95-419 | - | |
| psp00738 | nucleocapsid protein 49-364 | 49-364 | - | |
| psp00929 | nucleocapsid protein ΔSR (176-206) | 1-175, 207-419 | - | |
| psp01243 | nucleocapsid protein d_IDR2 | 1-127, 298-419 | - | |
| psp01436 | nucleocapsid protein d_RBD | 1-49, 175-419 | - | |
| psp01610 | nucleocapsid protein (Δ176-246) | 1-175, 247-419 | - | |
| psp01623 | nucleocapsid protein 1-364 | 1-364 | - | |
| psp01674 | nucleocapsid protein (1-174) | 1-174 | - | |
| psp01735 | nucleocapsid protein 49-419 | 49-419 | - | |
| psp01889 | nucleocapsid protein 1-246 | 1-246 | - | |
| psp02020 | nucleocapsid protein (Δlinker 175-247) | 1-174, 248-419 | - | |
| psp02770 | nucleocapsid protein d_IDR3 | 1-352 | - | |
| psp03256 | nucleocapsid protein (40-174) | 40-174 | - | |
| psp03595 | nucleocapsid protein d_DD | 1-245, 366-419 | - | |
| psp03665 | nucleocapsid protein (ΔCIDR 367-419) | 1-366 | - | |
| psp04055 | nucleocapsid protein Δ210-246 | 1-209, 247-419 | - | |
| psp04711 | nucleocapsid protein (176-419) | 176-419 | - | |
| psp04732 | nucleocapsid protein (ΔNTD 44-174) | 1-43, 175-419 | - | |
| psp04790 | nucleocapsid protein (175-364) | 175-364 | - | |
| psp05084 | nucleocapsid protein (ΔNIDR 1-43) | 44-419 | - | |
| psp00414 | nucleocapsid protein K375E | - | K375E | |
| psp00784 | nucleocapsid protein K375N | - | K375N | |
| psp00896 | nucleocapsid protein 11SD in SR | - | S176D, S180D, S183D, S184D, S186D, S187D, S188D, S190D, S193D, S194D, S197D | |
| psp03038 | nucleocapsid protein Y109A | - | Y109A | |
| psp04853 | nucleocapsid protein 14SA in SR | - | S176A, S180A, S183A, S184A, S186A, S187A, S188A, S190A, S193A, S194A, S197A, S201A, S202A, S206A |
Orthologs and Paralogs
| ID | Name | Organism | Length |
|---|---|---|---|
| psp03134 | Nucleoprotein | Human coronavirus | 441 |
| psp04689 | Nucleoprotein | Severe acute | 422 |
| psp00357 | Nucleoprotein | Human coronavirus | 377 |
| psp00312 | Nucleoprotein | MERS-CoV | 411 |
| psp01195 | Nucleoprotein | Human coronavirus | 389 |
| psp01517 | Nucleoprotein | Human coronavirus | 448 |
Biophysical Features
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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.
Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.
PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.
LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.
NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.
Polarity was computated by ProtScale, please refer to: ProtScale.
SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.
Protein Structure
Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.
For pLDDT, please refer to: pLDDT: Understanding local confidence