DCP5 ICS (YW-S)
Protein Sequence
Sequence Variants
| ID | Name | Remain region | Mutation sites | Ref seq |
|---|---|---|---|---|
| psp04617 | DCP5 | 1-611 | - | ✓ |
| psp03977 | DCP5 ICS (YW-S) | 92-301 | Y112S, Y154S, W163S, Y172S, W173S, Y177S, Y211S | |
| psp00389 | DCP5 IDR123 | 93-301 | - | |
| psp01114 | DCP5 ΔN | 89-611 | - | |
| psp01683 | DCP5 ΔPrLD2 | 1-563 | - | |
| psp02489 | DCP5 ΔIDR123 | 1-90, 303-611 | - | |
| psp02854 | DCP5 ΔC | 1-458 | - | |
| psp03221 | DCP5 ΔIDR1234 | 1-90, 364-611 | - | |
| psp03888 | DCP5 ICS (CR deleted) | 93-94, 98-115, 117-118, 121-153, 155-161, 163-167, 169-188, 190-192, 194-198, 202-248, 250-301 | - | |
| psp03942 | DCP5 ΔPrD | 1-133, 228-574 | - | |
| psp04267 | DCP5 ΔIDR12 | 1-90, 240-611 | - | |
| psp04505 | DCP5 ΔIDR1 | 1-90, 155-611 | - | |
| psp04675 | DCP5 ΔIDR | 1-90, 454-611 | - | |
| psp04760 | DCP5 ΔIDR45 | 1-301, 454-611 | - | |
| psp00594 | DCP5 ICS 23 (L to N) | 93-301 | L122N, L130N, L153N, L160N, L184N, L187N, L192N, L199N, L205N, L209N, L226N, L231N, L238N, L248N, L253N, L258N, L263N, L267N, L271N, L279N, L287N, L288N, L300N | |
| psp00684 | DCP5 ICS (F-Y) | 92-301 | F147Y, F176Y, F214Y, F239Y, F241Y, F255Y | |
| psp00923 | DCP5 ICS 23 (L to A) | 92-299, 347-348 | L122A, L130A, L153A, L160A, L184A, L187A, L192A, L199A, L205A, L209A, L226A, L231A, L238A, L248A, L253A, L258A, L263A, L267A, L271A, L279A, L287A, L288A | |
| psp01522 | DCP5 ICS 23 (L to D) | 92-299, 529-529, 537-537 | L122D, L130D, L153D, L160D, L184D, L187D, L192D, L199D, L205D, L209D, L226D, L231D, L238D, L248D, L253D, L258D, L263D, L267D, L271D, L279D, L287D, L288D | |
| psp02856 | DCP5 ICS 12 (L to N) | 92-301 | L122N, L153N, L184N, L192N, L205N, L226N, L238N, L253N, L263N, L271N, L287N, L300N | |
| psp03249 | DCP5 ICS 6 (L to N) | 92-301 | L122N, L184N, L205N, L238N, L258N, L279N | |
| psp04763 | DCP5 ICS (CR substituted) | 92-301 | P93T, M116Q, S119A, G120S, Y154F, S162A, Q168L, Q189L, I193Q, L199Q, M201Q, P202T, A249S | |
| psp04871 | DCP5 ICS 10 (N to L) | 93-301 | N102L, N103L, N137L, N149L, N159L, N182L, N203L, N213L, N215L, N290L | |
| psp00282 | DCP5 ICS (scrambled 1#) | - | - | |
| psp01190 | DCP5 ICS (scrambled 3#) | - | - | |
| psp01992 | DCP5 ICS (scrambled 2#) | - | - |
Orthologs and Paralogs
| ID | Name | Organism | Length |
|---|---|---|---|
| psp02269 | LSm14A | Homo sapiens | 463 |
| psp04468 | DCP1 | Drosophila melanogaster | 372 |
| psp01629 | DCP5 | Chlamydomonas reinhardtii | 423 |
| psp01454 | DCP5 | Solanum lycopersicum | 566 |
| psp02829 | PAB8 | Arabidopsis thaliana | 671 |
| psp01232 | AT4G34110 | Arabidopsis thaliana | 629 |
| psp03575 | DCP2 | Homo sapiens | 420 |
| psp05123 | DCP5 | Physcomitrium patens | 666 |
| psp00274 | DCP1 | Arabidopsis thaliana | 367 |
| psp03994 | DCP5 | Oryza sativa | 690 |
| psp01966 | AT2G23350 | Arabidopsis thaliana | 662 |
| psp00734 | Dcp2 | Saccharomyces cerevisiae | 970 |
| psp00565 | RAP55 | Xenopus laevis | 471 |
| psp01140 | Scd6p | Saccharomyces cerevisiae | 349 |
| psp04576 | DCP1A | Homo sapiens | 582 |
| psp01851 | Dcp1 | Saccharomyces cerevisiae | 231 |
| psp00891 | DCP1A (CTD) | Homo sapiens | 202 |
| psp03215 | DCP1A (NTD) | Homo sapiens | 380 |
| psp01072 | Dcp1 Δ82-129 | Saccharomyces cerevisiae | 183 |
| psp02213 | Dcp2 301-970 | Saccharomyces cerevisiae | 670 |
| psp03639 | Dcp2 1-300 | Saccharomyces cerevisiae | 300 |
Biophysical Features
The chart can zoom in and zoom out by mouse wheel.
IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.
Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.
PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.
LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.
NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.
Polarity was computated by ProtScale, please refer to: ProtScale.
SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.
Protein Structure
Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.
For pLDDT, please refer to: pLDDT: Understanding local confidence