PYCO1 46RC

ID psp01670
Organism Phaeodactylum tricornutum
Length 316

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
39326491 Negative -

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp02341 PYCO1 1-595 - ✓
psp01670 PYCO1 46RC 1-1, 281-595 -
psp00619 PYCO1 45R 1-1, 281-441, 583-595 -
psp00656 PYCO1 2,6R 1-1, 163-237, 441-522, 583-595 -
psp01017 PYCO1 56RC 1-1, 359-595 -
psp01249 PYCO1 23R 1-1, 163-280, 583-595 -
psp01325 PYCO1 36RC 1-1, 236-595 -
psp01841 PYCO1 26RC 1-1, 163-595 -
psp02104 PYCO1 34R 1-1, 236-360, 583-595 -
psp02605 PYCO1 1,6R 1-1, 83-160, 440-522, 583-595 -
psp02855 PYCO1 12R 1-1, 83-238, 583-595 -
psp02861 PYCO1 6RC 1-20, 442-595 -
psp02877 PYCO1 56R 1-1, 359-522, 583-595 -
psp01864 PYCO1 56R W476A 1-1, 359-522, 583-595 W466A
psp02186 PYCO1 56R Y471A/W476A 1-1, 359-522, 583-595 Y461A, W466A
psp04076 PYCO1 56R R470A/R479A 1-1, 359-522, 583-595 R460A, R469A
psp04211 PYCO1 56R K469A/K475A 1-1, 359-522, 583-595 K459A, K465A
psp05045 PYCO1 56R Y431A/Y444A 1-1, 359-522, 583-595 Y421A, Y433A

Orthologs and Paralogs

ID Name Organism Length
psp03426 PYCO1 Phaeodactylum tricornutum 592
psp00415 PYCO1(W→A) Phaeodactylum tricornutum 592
psp00469 PYCO1(W/Y→A) Phaeodactylum tricornutum 592
psp01185 PYCO1(Y→A) Phaeodactylum tricornutum 592

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence