TDRD1
Synonyms: tdrd1, Tudor domain-containing protein 1 isoform X2
Protein Sequence
Sequence Variants
Orthologs and Paralogs
| ID | Name | Organism | Length |
|---|---|---|---|
| psp00674 | Vret | Drosophila melanogaster | 642 |
| psp03691 | Kots | Drosophila melanogaster | 892 |
| psp03502 | TDRD1 | Homo sapiens | 1180 |
| psp00260 | TDRD1 | Gallus gallus | 1035 |
| psp01007 | TDRD1 | Alligator sinensis | 1165 |
| psp04659 | TDRD1 | Danio rerio | 1175 |
| psp03075 | TDRD1 | Mus musculus | 1172 |
| psp02999 | Veneno | Drosophila melanogaster | 691 |
| psp02867 | DmVeneno+mouse TDRD1 CTD | synthetic | 751 |
| psp03821 | DmVret+mouse TDRD1 CTD | synthetic | 702 |
| psp03905 | DmKots+mouse TDRD1 CTD | synthetic | 952 |
| psp00168 | TDRD1-3GS (1149-1154 GSGSGS) | Mus musculus | 1172 |
| psp01799 | TDRD-1 GS-1 | Mus musculus | 1172 |
| psp02107 | TDRD-1 GS-2 | Mus musculus | 1172 |
| psp02123 | TDRD1 I1149E | Mus musculus | 1172 |
| psp02349 | TDRD1 Y554L&Y774L | Mus musculus | 1172 |
| psp02760 | TDRD1 Y774L | Mus musculus | 1172 |
| psp02995 | TDRD1-6A | Mus musculus | 1172 |
| psp03449 | TDRD1 F1152E | Mus musculus | 1172 |
| psp03519 | TDRD-1 GS-3 | Mus musculus | 1172 |
| psp04316 | TDRD1 L1154E | Mus musculus | 1172 |
| psp04620 | TDRD1 L1153E | Mus musculus | 1172 |
| psp04699 | TDRD1 L1150E | Mus musculus | 1172 |
| psp05103 | TDRD1 L1151E | Mus musculus | 1172 |
| psp05180 | TDRD1 Y554L | Mus musculus | 1172 |
| psp00095 | TDRD1 ΔTD2 | Mus musculus | 957 |
| psp00145 | TDRD1-ΔNTD | Mus musculus | 1043 |
| psp00388 | TDRD1 TD2+CTD | Mus musculus | 313 |
| psp00593 | TDRD1 1-1140 | Mus musculus | 1140 |
| psp01499 | TDRD1 ΔTD | Mus musculus | 290 |
| psp01533 | TDRD1 ΔTD1 | Mus musculus | 962 |
| psp01955 | TDRD1 1-1155 | Mus musculus | 1155 |
| psp02053 | TDRD1-ΔIDR | Mus musculus | 942 |
| psp02145 | TDRD1 TD1+CTD | Mus musculus | 323 |
| psp02221 | TDRD1 ΔTD4 | Mus musculus | 974 |
| psp02362 | TDRD1 ΔTD3 | Mus musculus | 971 |
| psp02808 | TDRD1 1-1160 | Mus musculus | 1160 |
| psp03096 | TDRD1 1-1145 | Mus musculus | 1145 |
| psp04394 | TDRD1 TD4+CTD | Mus musculus | 267 |
| psp04405 | TDRD1 1-1150 | Mus musculus | 1150 |
| psp04809 | TDRD1 TD3+CTD | Mus musculus | 318 |
| psp05013 | TDRD TD234+CTD | Mus musculus | 712 |
| psp05097 | TDRD TD34+CTD | Mus musculus | 492 |
Biophysical Features
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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.
Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.
PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.
LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.
NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.
Polarity was computated by ProtScale, please refer to: ProtScale.
SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.
Protein Structure
Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.
For pLDDT, please refer to: pLDDT: Understanding local confidence