MBP-52K (S28/75D)

ID psp03297
Organism Adenovirus
Length 789

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
38177504 Negative -

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp00358 MBP-52K 1-789 - ✓
psp03297 MBP-52K (S28/75D) - S402D, S449D
psp03631 MBP-52K (S28/75A) - S402A, S449A

Orthologs and Paralogs

ID Name Organism Length
psp03460 52K Human adenovirus 415
psp03489 52K (S28/75A) Adenovirus 415
psp04032 52K (S28/75D) Adenovirus 415
psp01257 52K Human adenovirus 5 415
psp00754 52K (R/K) Human adenovirus 5 415
psp01054 52K (Scramble) Human adenovirus 5 415
psp01899 52K (P/A) Human adenovirus 5 415
psp04603 52K (Q/G) Human adenovirus 5 415
psp02098 52K (Δ1-47) Human adenovirus 5 368
psp00560 MBP-GATA3 Homo sapiens 817
psp01113 MBP-yCTD Saccharomyces cerevisiae 559
psp01969 MBP-CHOP Synthetic 575
psp03700 MBP-IDPC-2 Caenorhabditis elegans 690
psp04164 MBP-hCTD Homo sapiens 745
psp02233 MBP Synthetic 367
psp04983 MBP Synthetic 367
psp00026 MBP-PdhR-FUSN Synthetic 903
psp01503 MBP-FUS-CHOP Synthetic 750
psp02805 MBP-FUS Homo sapiens 928
psp04126 MBP-FUSN Synthetic 649
psp00625 MBP-RGG-RGG Synthetic 711
psp03267 MBP-RGG-SmBit-RGG Caenorhabditis elegans 843
psp03300 MBP-RGG-LgBit-RGG Caenorhabditis elegans 909

Biophysical Features

The chart can zoom in and zoom out by mouse wheel.

IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence