PHF13 (Δ24-40)

ID psp00424
Organism Homo sapiens
Length 283

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
40598901 - Negative

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp04511 PHF13 1-300 - ✓
psp00424 PHF13 (Δ24-40) 1-23, 41-300 -
psp00213 PHF13 (Δ24-40, Δ272-280) 1-23, 41-271, 281-300 -
psp03216 PHF13 (Δ24-40, Δ232-238) 1-23, 41-231, 239-300 -
psp04867 PHF13 ΔPEST2 1-140, 191-300 -

Orthologs and Paralogs

ID Name Organism Length
psp05026 PHF6 Homo sapiens 365
psp04993 PHF1 Homo sapiens 567
psp01199 PHF1 H115A Homo sapiens 567
psp01932 PHF1 K323A Homo sapiens 567
psp03801 PHF1 Y47A Homo sapiens 567
psp00819 PHF1 (1-511) Homo sapiens 511
psp00925 PHF1 (1-396) Homo sapiens 369
psp01315 PHF1 (330-511) Homo sapiens 182
psp02873 PHF1 (1-355) Homo sapiens 355
psp02983 PHF1 (28-567) Homo sapiens 540
psp03246 PHF1 (233-567) Homo sapiens 335
psp03378 PHF1 (330-567) Homo sapiens 238
psp03889 PHF1 IDR (337-529) Homo sapiens 193
psp04131 PHF1 (86-567) Homo sapiens 482
psp00061 GST-PHF13 Homo sapiens 518

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence