CD2AP ΔCC

ID psp05137
Organism Homo sapiens
Length 416

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
34330769 Negative -

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp00481 CD2AP 1-639 - ✓
psp05137 CD2AP ΔCC 1-416 -
psp00259 CD2AP ΔSH3 331-639 -
psp03604 CD2AP ΔPR 1-337, 417-639 -
psp03859 CD2AP ΔP1-3 1-337, 345-387, 395-409, 417-639 -

Orthologs and Paralogs

No orthologs or paralogs found for this protein in the database.

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence