Cdt1 Ile/Leu(1.0)

ID psp04943
Organism Drosophila melanogaster
Length 743

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
34951585 Positive -

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp02325 Cdt1 1-743 - ✓
psp04943 Cdt1 Ile/Leu(1.0) - L18A, I22A, I24A, L29A, L45A, L54A, L57A, L74A, I75A, I96A, L101A, I105A, L110A, L121A, L126A, I132A, I143A, L156A, I163A, L164A, I170A, L174A, L178A, L193A, L196A, L200A, L202A, L206A, L220A, L236A, I242A, L244A, L247A, I248A, L251A, I260A, L270A, L282A, L283A, L295A
psp00419 Cdt1 IDR 1-321 -
psp04805 Cdt1 ΔIDR 322-743 -
psp00572 Cdt1 (F to L) - F9L, F10L, F104L, F141L, F180L, F239L, F254L, F284L
psp02281 Cdt1 Ile/Leu(0.5) - L18A, I22A, L45A, L57A, I75A, L101A, I105A, L121A, I143A, L156A, I163A, L174A, L193A, L200A, L206A, L236A, I242A, L247A, I260A, L270A, L283A
psp04691 Cdt1 (F to A) - F9A, F10A, F104A, F141A, F180A, F239A, F254A, F284A
psp02745 Cdt1 ScrIDR - -

Orthologs and Paralogs

ID Name Organism Length
psp00107 Cdt1 Homo sapiens 546

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence