Axin

Synonyms: dAxin, Axn, Axin, Axis inhibition protein, CG7926, d-Axin

ID psp04239
Organism Drosophila melanogaster
Length 745
Source UniProt: Q9V407

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
32129710 - Positive

Protein Sequence

Sequence Variants

No protein variants available for this protein.

Orthologs and Paralogs

ID Name Organism Length
psp03995 Axin1 Mus musculus 863
psp04148 Axin1 Homo sapiens 862
psp00046 Axin Δ465-496 Homo sapiens 830
psp00184 Axin 209-530 Homo sapiens 322
psp00296 Axin Δ531-679 Homo sapiens 713
psp00328 Axin1 AD5 Homo sapiens 635
psp00643 Axin1 AD2 Homo sapiens 635
psp00683 Axin1 AD3 Homo sapiens 379
psp00990 Axin1 AD9 Homo sapiens 796
psp01176 Axin1 AD4 Homo sapiens 831
psp02275 Axin1 AD6 Homo sapiens 805
psp02617 Axin1 AD1 Homo sapiens 606
psp02625 Axin1 AD7 Homo sapiens 694
psp03022 Axin Δ209-464+Δ497-679 Homo sapiens 423
psp03410 Axin 209-679 Homo sapiens 471
psp03567 Axin Δ209-679 Homo sapiens 391
psp03790 Axin1 AD10 Homo sapiens 836
psp01711 Axin1 AD7-hnRNPA1 Homo sapiens 829
psp01761 Axin1 AD7-TDP43 Homo sapiens 842

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence