Efg1 ΔDBD Y64S/Y66S/Y69S

ID psp04105
Organism Candida albicans
Length 374

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
38297837 Positive -

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp03348 Efg1 1-550 - ✓
psp04105 Efg1 ΔDBD Y64S/Y66S/Y69S 1-180, 357-550 Y64S, Y66S, Y69S
psp00346 Efg1 DBD 181-356 -
psp02219 Efg1 ΔDBD 1-180, 357-550 -
psp03182 Efg1 C-PrLD 357-550 -
psp03316 Efg1 N-PrLD 1-180 -
psp00197 Efg1 ΔDBD A51P/A56P/Q70P/N102P/Q443P 1-180, 357-550 A51P, A56P, Q70P, N102P, Q443P
psp01769 Efg1 ΔDBD Y401S/Y404S/Y409S 1-180, 357-550 Y401S, Y404S, Y409S
psp02485 Efg1 ΔDBD Q443P 1-180, 357-550 Q443P
psp02616 Efg1 ΔDBD Y115S/Y132S/Y139S 1-180, 357-550 Y115S, Y132S, Y139S
psp02717 Efg1 ΔDBD Y4S/Y8S/Y16S 1-180, 357-550 Y4S, Y8S, Y16S
psp02777 Efg1 ΔDBD Y101S/Y104S/Y106S 1-180, 357-550 Y101S, Y104S, Y106S
psp03161 Efg1 ΔDBD A51P/A56P 1-180, 357-550 A51P, A56P
psp04567 Efg1 ΔDBD A51P/A56P/Q443P 1-180, 357-550 A51P, A56P, Q443P
psp04609 Efg1 ΔDBD A51P/A56P/Q70P/Q443P 1-180, 357-550 A51P, A56P, Q70P, Q443P

Orthologs and Paralogs

No orthologs or paralogs found for this protein in the database.

Biophysical Features

The chart can zoom in and zoom out by mouse wheel.

IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence