G3BP2
Synonyms: SH3 domain binding protein 2, fb43h08, Zgc:158370, g3bp2a, Ras GTPase-activating protein-binding protein 2, g3bp2, fe25b02
Protein Sequence
Orthologs and Paralogs
| ID | Name | Organism | Length |
|---|---|---|---|
| psp03170 | G3BP1 | Mus musculus | 465 |
| psp04744 | G3BP1 | Homo sapiens | 466 |
| psp01096 | G3BP2a | Homo sapiens | 482 |
| psp02160 | G3BP2B | Homo sapiens | 449 |
| psp01815 | G3BP1 | Danio rerio | 477 |
| psp00195 | G3BP1 ΔRBD+YTHDF3(417-550) | Synthetic | 469 |
| psp00661 | G3BP1 ΔRBD+RBMS2(56-220) | Synthetic | 500 |
| psp00688 | G3BP1 ΔRBD+DAZAP1(10-190) | Synthetic | 516 |
| psp00752 | G3BP1 ΔRBD+YTHDF2(411-544) | Synthetic | 469 |
| psp00884 | G3BP1 ΔRBD+SRSF4(2-177) | Synthetic | 512 |
| psp01739 | G3BP1 ΔRBD+hnRNPA2B1 (7-179) | Synthetic | 507 |
| psp01813 | G3BP1 ΔRBD+hnRPNH2(11-188) | Synthetic | 513 |
| psp02258 | G3BP1 ΔRBD+STAU1(186-353) | Synthetic | 503 |
| psp02355 | G3BP1 ΔRBD+ADAR1(504-792) | Synthetic | 624 |
| psp02851 | G3BP1 ΔRBD+ZC3H11A(2-110) | Synthetic | 444 |
| psp02971 | G3BP1 ΔRBD+YTHDF1(390-523) | Synthetic | 469 |
| psp03035 | G3BP1 ΔRBD+hnRNPD(99-257) | Synthetic | 494 |
| psp03194 | BFP-G3BP1 | Homo sapiens | 704 |
| psp03605 | G3BP1 ΔRBD+RBM22(159-185) | Synthetic | 362 |
| psp03795 | G3BP1 ΔRBD+hnRNPA1 (12-181) | Synthetic | 505 |
| psp05166 | G3BP1 ΔRBD+TDP-43(105-261) | Synthetic | 492 |
| psp00904 | G3BP1 F33W | Homo sapiens | 466 |
| psp01040 | G3BP1 EQ28 | Homo sapiens | 466 |
| psp01125 | G3BP1 G96A | Homo sapiens | 466 |
| psp01682 | G3BP1 11RK | Homo sapiens | 466 |
| psp02100 | G3BP1 S38F | Homo sapiens | 466 |
| psp02622 | G3BP1 Y34A | Homo sapiens | 466 |
| psp03117 | G3BP1 S149A | Homo sapiens | 466 |
| psp04715 | G3BP1 S149E | Homo sapiens | 466 |
| psp00177 | G3BP1 ∆RGG | Homo sapiens | 410 |
| psp00679 | G3BP1 ∆IDR1/2 | Homo sapiens | 273 |
| psp01202 | G3BP1 (411-466) | Homo sapiens | 56 |
| psp01227 | G3BP1 ΔRBD (1-335) | Homo sapiens | 335 |
| psp01230 | G3BP1 ∆IDR1 | Homo sapiens | 382 |
| psp01360 | G3BP1 Δ340-415 | Homo sapiens | 390 |
| psp03226 | G3BP1 (ΔNTF) | Homo sapiens | 333 |
| psp03272 | G3BP1 ∆RRM | Homo sapiens | 389 |
| psp03824 | G3BP1 ΔIDR3 (Δ428-466) | Homo sapiens | 427 |
| psp04415 | G3BP1 ∆IDR2 | Homo sapiens | 357 |
| psp04677 | G3BP1 (ΔRG) | Homo sapiens | 424 |
| psp04702 | G3BP1 ΔIDR1/2 (Δ142-335) | Homo sapiens | 272 |
| psp04761 | G3BP1 ∆RBD | Homo sapiens | 334 |
| psp04869 | G3BP1 ∆NTF2 | Homo sapiens | 324 |
| psp04898 | G3BP1 (ΔE1ΔE2) | Homo sapiens | 406 |
Biophysical Features
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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.
Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.
PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.
LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.
NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.
Polarity was computated by ProtScale, please refer to: ProtScale.
SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.
Protein Structure
Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.
For pLDDT, please refer to: pLDDT: Understanding local confidence