p53 (95-356)
Protein Sequence
Sequence Variants
| ID | Name | Remain region | Mutation sites | Ref seq |
|---|---|---|---|---|
| psp03918 | p53 | 1-393 | - | ✓ |
| psp03514 | p53 (95-356) | 95-356 | - | |
| psp00019 | p53 ΔUBR | 1-292 | - | |
| psp00111 | p53 (326-393) | 326-393 | - | |
| psp00186 | p53 d_TD | 1-306, 356-393 | - | |
| psp00285 | p53 d_DBD | 1-99, 301-393 | - | |
| psp00315 | p53 (357-393) | 357-393 | - | |
| psp01126 | p53 (1-356) | 1-356 | - | |
| psp01461 | p53 TetCT (293-393) | 293-393 | - | |
| psp01724 | p53 CoreTetCT (94-393) | 94-393 | - | |
| psp01833 | p53 d_CTD | 1-355 | - | |
| psp02895 | p53 (95-393) | 95-393 | - | |
| psp03509 | p53 NCT 1-363 | 1-363 | - | |
| psp03711 | p53 d_TAD | 93-393 | - | |
| psp03895 | p53 (1-94) | 1-94 | - | |
| psp04231 | p53 (1-325) | 1-325 | - | |
| psp04318 | p53C | 94-312 | - | |
| psp00562 | p53 (K139T) | - | K139T | |
| psp01758 | p53 S392D | - | S392D | |
| psp01795 | p53 (K139N) | - | K139N | |
| psp02248 | p53 L344P | - | L344P | |
| psp02277 | p53 L344A | - | L344A | |
| psp02388 | p53 S392E | - | S392E | |
| psp02590 | p53 S392A | - | S392A | |
| psp03823 | p53 (K120N) | - | K120N | |
| psp03899 | p53 (K139E) | - | K139E | |
| psp04430 | p53 (K139Q) | - | K139Q | |
| psp04685 | p53 (K120Q) | - | K120Q | |
| psp04726 | p53 (K120E) | - | K120E | |
| psp00356 | p53 UBR-R337H | 293-393 | R337H | |
| psp01187 | p53 UBR-R337C | 293-393 | R337C | |
| psp02344 | p53 UBR-R337P | 293-393 | R337P | |
| psp02735 | p53 UBR-L344P | 293-393 | L344P | |
| psp03490 | p53C R175H | 94-312 | R175H | |
| psp04854 | p53C R248Q | 94-312 | R248Q |
Orthologs and Paralogs
Biophysical Features
The chart can zoom in and zoom out by mouse wheel.
IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.
Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.
PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.
LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.
NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.
Polarity was computated by ProtScale, please refer to: ProtScale.
SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.
Protein Structure
Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.
For pLDDT, please refer to: pLDDT: Understanding local confidence