SS18

Synonyms: Syt, Protein SSXT, Ss18, Synovial sarcoma-associated Ss18-alpha, Protein SYT, Ssxt

ID psp03435
Organism Mus musculus
Length 418
Source UniProt: Q62280

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
34215745 Positive Positive

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp03435 SS18 1-418 -

Orthologs and Paralogs

ID Name Organism Length
psp03421 SS18 Homo sapiens 418
psp00468 SS18 Homo sapiens 387
psp01744 SS18-SSX1 Homo sapiens 488
psp03549 SS18 PLD Homo sapiens 352
psp00326 SS18 21YtoS Homo sapiens 387
psp03559 SS18 I32E, L54E, A65E Homo sapiens 387
psp02468 SS18-SSX1 Homo sapiens 456
psp01412 SS18(3M)-SSX1 Homo sapiens 456
psp02650 SS18(Y19S)-SSX1 Homo sapiens 456

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence