Pat1

Synonyms: Topoisomerase II-associated protein PAT1, YCR077C, Deadenylation-dependent mRNA-decapping factor PAT1, Decapping activator and translational repressor PAT1, mRNA turnover protein 1, YCR77C, DNA topoisomerase 2-associated protein PAT1, MRT1, PAT1

ID psp03308

Organism Saccharomyces cerevisiae

Length 796

Source UniProt: P25644

PS Record in Articles

Reference (Pubmed ID)	In vitro results	In vivo results
32553117	-	Positive
36972455	Positive	-

Protein Sequence

Sequence Variants

ID	Name	Remain region	Mutation sites	Ref seq
psp03308	Pat1	1-796	-	✓
psp03738	Pat1 423-796	423-796	-
psp04014	Pat1 241-422	241-422	-
psp04903	Pat11-240	1-240	-

Orthologs and Paralogs

No orthologs or paralogs found for this protein in the database.

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence