YY1 cIDR

ID psp03273
Organism Homo sapiens
Length 38

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
35390165 Positive Positive

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp04028 YY1 1-414 - ✓
psp03273 YY1 cIDR 43-80 -
psp00992 YY1 IDR 21-318 -
psp01178 YY1(ΔG) 1-53, 70-414 -
psp01625 YY1 24-318 24-318 -
psp02751 YY1-IDR 1-210 -
psp02926 YY1 non-IDR 319-414 -
psp03537 YY1(ΔH) 1-69, 81-414 -
psp04350 YY1(ΔE/D) 1-42, 54-414 -
psp04888 YY1(ΔcIDR) 1-42, 81-414 -
psp05186 YY1 (Δ24-318) 1-23, 319-414 -
psp00963 YY1 Y8F, Y383F - Y8F, Y383F
psp02403 YY1-6R - K173R, K174R, K178R, K179R, K182R, K183R
psp02994 YY1(G-A) - G54A, G55A, G56A, G57A, D58A, H59A, G60A, G61A, G62A, G63A, G64A, H65A, G66A, H67A, G69A
psp03097 YY1 Y145F, Y185F, Y251F, Y254F - Y145F, Y185F, Y251F, Y254F
psp03459 YY1(H-A) - H70A, H71A, H72A, H73A, H74A, H75A, H76A, H77A, H78A, H79A, H80A
psp03505 YY1(E/D-A) - E43A, E44A, E45A, E46A, E47A, D48A, D49A, D50A, D51A, E52A, D53A

Orthologs and Paralogs

No orthologs or paralogs found for this protein in the database.

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence