FMR1 R138Q

ID psp03225
Organism Homo sapiens
Length 632

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
40588021 Positive -

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp03946 FMR1 1-632 - ✓
psp03225 FMR1 R138Q - R138Q
psp00701 FMR1 C-terminus 445-632 -
psp00004 FMR1 (V427P) - V427P
psp01100 FMR1 (G266E) - G266E
psp02109 FMR1 (I304N) - I304N

Orthologs and Paralogs

No orthologs or paralogs found for this protein in the database.

Biophysical Features

The chart can zoom in and zoom out by mouse wheel.

IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence