TRIM6 L148P

ID psp02759
Organism Homo sapiens
Length 488

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
40450692 - Negative

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp00672 TRIM6 1-488 - ✓
psp02759 TRIM6 L148P - L148P
psp04027 TRIM6 ΔCC 1-133, 249-488 -
psp04272 TRIM6 C15A - C15A

Orthologs and Paralogs

ID Name Organism Length
psp01067 TRIM32 Homo sapiens 653
psp02563 TRIM26 Homo sapiens 539
psp03277 TRIM23 Homo sapiens 574
psp03190 TRIM29 Homo sapiens 588
psp04845 TRIM31 Homo sapiens 425
psp01358 TRIM37 Homo sapiens 964
psp00566 TRIM38 Homo sapiens 465
psp01715 TRIM41 Homo sapiens 630
psp02128 TRIM65 Homo sapiens 517
psp01214 TRIM8 Homo sapiens 551
psp01254 TRIM47 Homo sapiens 638
psp02712 TRIM35 Homo sapiens 493
psp05140 TRIM34 Homo sapiens 488
psp00012 TRIM33 Homo sapiens 1127
psp03008 TRIM18 Homo sapiens 667
psp01294 TRIM54 Homo sapiens 358
psp02703 TRIM63 Homo sapiens 353
psp01472 TRIM55 Homo sapiens 548
psp01312 TRIM19 Homo sapiens 882
psp03760 TRIM49B Homo sapiens 452
psp05102 TRIM61 Homo sapiens 209
psp03063 TRIM69 Homo sapiens 500
psp05052 TRIM48 Homo sapiens 224
psp04899 TRIM52 Homo sapiens 297
psp00303 TRIM59 Homo sapiens 403
psp01478 TRIM25 Homo sapiens 630
psp03675 TRIM49 Homo sapiens 452
psp05115 TRIM60 Homo sapiens 471
psp01075 TRIM40 Homo sapiens 258
psp00739 TRIM2 Homo sapiens 744
psp02519 TRIM4 Homo sapiens 500
psp04246 TRIM45 Homo sapiens 580
psp01765 TRIM13 Homo sapiens 407
psp04141 TRIM68 Homo sapiens 485
psp01264 TRIM17 Homo sapiens 477
psp00396 TRIM5α Homo sapiens 493
psp00691 TRIM11 Homo sapiens 468
psp02567 TRIM36 Homo sapiens 728
psp01608 TRIML2 Homo sapiens 437
psp01614 TRIM76 Homo sapiens 4069
psp00765 TRIM39 Homo sapiens 518
psp02967 TRIM46 Homo sapiens 759
psp03580 TRIM10 Homo sapiens 481
psp05163 TRIM14 Homo sapiens 442
psp03245 TRIM20 Homo sapiens 781
psp02990 TRIM22 Homo sapiens 498
psp02858 TRIM24 Homo sapiens 1050
psp01552 TRIM24 short Homo sapiens 1016
psp04640 TRIM27 Homo sapiens 513
psp04531 TRIM3 Homo sapiens 744
psp04777 TRIM50 Homo sapiens 487
psp03564 TRIM73 Homo sapiens 250
psp03924 TRIM62 Homo sapiens 475
psp04594 TRIM66 Homo sapiens 1351
psp03893 TRIM67 Homo sapiens 783
psp04861 TRIM7 Homo sapiens 511
psp02009 TRIM71 Homo sapiens 868
psp00769 TRIM72 Homo sapiens 477
psp01053 TRIM75 Homo sapiens 468
psp00868 TRIM77 Homo sapiens 450
psp01071 TRIM9 Homo sapiens 710
psp00052 TRIML1 Homo sapiens 468
psp04696 TRIM1 Homo sapiens 735
psp04607 TRIM16 Homo sapiens 564
psp01790 TRIM70 Homo sapiens 348
psp02797 TRIM21 Homo sapiens 475
psp01062 TRIM28 Homo sapiens 835
psp01435 TRIM42 Homo sapiens 723
psp04157 TRIM43 Homo sapiens 446
psp01346 TRIM44 Homo sapiens 344
psp05056 TRIM74 Homo sapiens 250
psp00563 TRIM51 Homo sapiens 452
psp04789 TRIM56 Homo sapiens 755
psp01292 TRIM58 Homo sapiens 486
psp01448 TRIM64 Homo sapiens 449
psp02733 TRIM15 Homo sapiens 465
psp00210 PML K160R Homo sapiens 882
psp00363 PML L268P/L298P Homo sapiens 882
psp00883 PML S518A Homo sapiens 882
psp00908 PML S117A Homo sapiens 882
psp01375 PML A216V Homo sapiens 882
psp02228 PML K490R Homo sapiens 882
psp02865 PML L217F Homo sapiens 882
psp03280 PML K65R Homo sapiens 882
psp03384 PML L332P Homo sapiens 882
psp03667 PML K515R Homo sapiens 882
psp03749 PML L298P Homo sapiens 882
psp04347 PML L268P Homo sapiens 882
psp04718 PML L218P Homo sapiens 882
psp04800 PML C213A Homo sapiens 882
psp04964 PML S214L Homo sapiens 882
psp04989 PML C66A Homo sapiens 882
psp01170 PML 1-256 Homo sapiens 256
psp04030 PML ∆CC Homo sapiens 744
psp02690 TRIM1 LDY-AAA Homo sapiens 735
psp02753 TRIM1 ΔCC Homo sapiens 666
psp00876 TRIM15 L137P Homo sapiens 465
psp01903 TRIM15 C16/19A Homo sapiens 465
psp03004 TRIM18 ΔCC Homo sapiens 607
psp03608 TRIM27 C16A Homo sapiens 513
psp00711 TRIM27 ΔCC Homo sapiens 472
psp01938 TRIM32 L163P Homo sapiens 653
psp03047 TRIM32 C20/23A Homo sapiens 653
psp04500 TRIM32 V184D Homo sapiens 653
psp04167 TRIM33 I840T Homo sapiens 1127
psp01441 TRIM34_43PS Homo sapiens 465
psp02592 TRIM34-43CC Homo sapiens 471
psp03687 TRIM34 C15A Homo sapiens 488
psp01582 TRIM34 ΔCC Homo sapiens 379
psp00583 TRIM38 F183P Homo sapiens 465
psp02105 TRIM38 L147P Homo sapiens 465
psp04897 TRIM38 L190P Homo sapiens 465
psp05124 TRIM38 C16A Homo sapiens 465
psp00432 TRIM38 ΔRING-B-box Homo sapiens 337
psp00652 TRIM38 ΔB-box Homo sapiens 423
psp01775 TRIM38 CC Homo sapiens 153
psp02684 TRIM38 ΔRING-B-box-CC Homo sapiens 184
psp03494 TRIM38 ΔCC Homo sapiens 302
psp04649 TRIM38 ΔPS Homo sapiens 281
psp05148 TRIM38 ΔRING Homo sapiens 378
psp01191 TRIM4 R478C Homo sapiens 500
psp05182 TRIM41 ΔCC Homo sapiens 520
psp02317 TRIM43_34CC Homo sapiens 463
psp03306 TRIM50 C16/19A Homo sapiens 487
psp05119 TRIM50 L185P Homo sapiens 487
psp02728 TRIM54 C26/29A Homo sapiens 358
psp00094 TRIM54 ΔCC Homo sapiens 319
psp00361 TRIM55 C26/29A Homo sapiens 548
psp05136 TRIM55 L193P Homo sapiens 548
psp02720 TRIM63 I130M Homo sapiens 353
psp01701 TRIM8 I207T Homo sapiens 551
psp00235 TRIM8 G401* Homo sapiens 401
psp02161 TRIM8 Q445* Homo sapiens 445
psp04424 TRIM8 Y487* Homo sapiens 487
psp02483 TRIM9 C30/33A Homo sapiens 710

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence