NuMA-N-C15

ID psp02203
Organism Homo sapiens
Length 1104

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
34887424 - Negative

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp00185 NuMA 1-2115 - ✓
psp02203 NuMA-N-C15 1-704, 1701-1910, 1926-2115 -
psp00002 NuMA-N-C (Δ705-1700) 1-704, 1701-2115 -
psp00292 NuMA (1826-1982) 1826-1982 -
psp01863 NuMA (1941-2115) 1941-2115 -
psp02333 NuMA-C 1699-2115 -
psp03155 NuMA-CT 1700-2115 1700-2115 -
psp04733 NuMA (1826-2115) 1826-2115 -
psp02480 NuMA-S1969D - S1969D
psp02696 NuMA-S1969A - S1969A
psp00727 NuMA-N-C5m 1-704, 1700-2115 P1911S, L1914S, W1917S, I1920S, L1923S
psp02924 NuMA-C-P/A 1699-2115 P1712A, P1716A, P1734A, P1742A, P1746A, P1752A, P1755A, P1758A, P1764A, P1765A, P1777A, P1779A, P1785A, P1828A, P1842A, P1863A, P1874A, P1878A, P1896A, P1897A, P1911A, P1931A, P1932A, P1939A, P1944A, P1961A, P1972A, P1994A, P1998A, P2001A, P2011A, P2013A, P2016A, P2036A, P2056A, P2078A, P2088A, P2107A

Orthologs and Paralogs

No orthologs or paralogs found for this protein in the database.

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence