UBQLN1
Synonyms: DA41, Protein linking IAP with cytoskeleton 1, PLIC-1, Ubiquilin-1, UBQLN1, hPLIC-1, PLIC1
PS Record in Articles
| Reference (Pubmed ID) | In vitro results | In vivo results |
|---|---|---|
| 33431932 | - | Positive |
| 38041404 | Positive | - |
Protein Sequence
Sequence Variants
| ID | Name | Remain region | Mutation sites | Ref seq |
|---|---|---|---|---|
| psp01732 | UBQLN1 | 1-589 | - | ✓ |
| psp03659 | UBQLN1 438-589 | 438-589 | - |
Orthologs and Paralogs
| ID | Name | Organism | Length |
|---|---|---|---|
| psp03543 | UBQLN4 | Homo sapiens | 601 |
| psp00678 | UBQLN2 | Homo sapiens | 624 |
| psp00943 | UBQLN2 (P497H) | Homo sapiens | 624 |
| psp01563 | UBQLN2 A282V | Homo sapiens | 624 |
| psp03204 | UBQLN2 P497S | Homo sapiens | 624 |
| psp04765 | UBQLN2 P506T | Homo sapiens | 624 |
| psp00633 | UBQLN2 430-624 | Homo sapiens | 195 |
| psp00725 | UBQLN2 ΔUBL | Homo sapiens | 518 |
| psp01052 | UBQLN2 ΔUBA | Homo sapiens | 576 |
| psp01403 | UBQLN2 575-624 | Homo sapiens | 50 |
| psp01686 | UBQLN2 Δ378-486 | Homo sapiens | 516 |
| psp02503 | UBQLN2 ΔUBLΔUBA | Homo sapiens | 468 |
| psp02635 | UBQLN2 450-624 | Homo sapiens | 175 |
| psp02881 | UBQLN2 ΔUBA | Homo sapiens | 575 |
| psp03346 | UBQLN2 ΔPXX | Homo sapiens | 577 |
| psp03892 | UBQLN2 ΔUBA | Homo sapiens | 580 |
| psp04200 | UBQLN2 487-624 | Homo sapiens | 138 |
| psp04962 | UBQLN2 1-106 | Homo sapiens | 106 |
| psp05050 | UBQLN2 ΔUBL | Homo sapiens | 516 |
| psp05086 | UBQLN2 (379-624) | Homo sapiens | 246 |
| psp00031 | UBQLN2 450-624 V564R | Homo sapiens | 175 |
| psp00596 | UBQLN2 450-624 P506R | Homo sapiens | 175 |
| psp00960 | UBQLN2 450-624 P506E | Homo sapiens | 175 |
| psp01003 | UBQLN2 (450-624) T487I | Homo sapiens | 175 |
| psp01103 | UBQLN2 (450-624) P506T | Homo sapiens | 175 |
| psp01314 | UBQLN2 450-624 V564L | Homo sapiens | 175 |
| psp01399 | UBQLN2 450-624 V538Q | Homo sapiens | 175 |
| psp01485 | UBQLN2 450-624 P497G | Homo sapiens | 175 |
| psp01617 | UBQLN2 450-624 V538G | Homo sapiens | 175 |
| psp01648 | UBQLN2 450-624 V564G | Homo sapiens | 175 |
| psp01720 | UBQLN2 450-624 P497R | Homo sapiens | 175 |
| psp01834 | UBQLN2 450-624 V564E | Homo sapiens | 175 |
| psp02002 | UBQLN2 (450-624) P497L | Homo sapiens | 175 |
| psp02036 | UBQLN2 (450-624) P497S | Homo sapiens | 175 |
| psp02048 | UBQLN2 (450-624) P525S | Homo sapiens | 175 |
| psp02217 | UBQLN2 450-624 P497Q | Homo sapiens | 175 |
| psp02270 | UBQLN2 450-624 P497E | Homo sapiens | 175 |
| psp02424 | UBQLN2 450-624 P506Q | Homo sapiens | 175 |
| psp03323 | UBQLN2 450-624 V538W | Homo sapiens | 175 |
| psp03425 | UBQLN2 450-624 V538E | Homo sapiens | 175 |
| psp03586 | UBQLN2 450-624 V538L | Homo sapiens | 175 |
| psp03635 | UBQLN2 450-624 V538R | Homo sapiens | 175 |
| psp03771 | UBQLN2 450-624 P525G | Homo sapiens | 175 |
| psp03830 | UBQLN2 450-624 P525L | Homo sapiens | 175 |
| psp03874 | UBQLN2 450-624 P525Q | Homo sapiens | 175 |
| psp03981 | UBQLN2 ΔUBL P506T | Homo sapiens | 518 |
| psp04258 | UBQLN2 450-624 P497W | Homo sapiens | 175 |
| psp04322 | UBQLN2 450-624 P506W | Homo sapiens | 175 |
| psp04398 | UBQLN2 450-624 P525W | Homo sapiens | 175 |
| psp04408 | UBQLN2 ΔUBA P506T | Homo sapiens | 575 |
| psp04701 | UBQLN2 450-624 P506G | Homo sapiens | 175 |
| psp04792 | UBQLN2 450-624 V564W | Homo sapiens | 175 |
| psp04802 | UBQLN2 450-624 P525E | Homo sapiens | 175 |
| psp04929 | UBQLN2 450-624 P506L | Homo sapiens | 175 |
| psp05022 | UBQLN2 450-624 V564Q | Homo sapiens | 175 |
| psp05033 | UBQLN2 450-624 P525R | Homo sapiens | 175 |
| psp00113 | UBQLN4 444-601 | Homo sapiens | 158 |
Biophysical Features
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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.
Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.
PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.
LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.
NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.
Polarity was computated by ProtScale, please refer to: ProtScale.
SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.
Protein Structure
Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.
For pLDDT, please refer to: pLDDT: Understanding local confidence