TAF15_RBD 181-589

ID psp01693
Organism Homo sapiens
Length 409

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
29961577 Positive -

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp01445 TAF15 1-592 - ✓
psp01693 TAF15_RBD 181-589 184-592 -
psp00403 TAF15_PLD 1-180 1-59, 63-183 -
psp00680 TAF15 (2-205) 2-205 -
psp00962 TAF15 1-208 1-208 -
psp01327 TAF15 1-59, 63-592 -
psp02905 TAF15_RBD_(6_repeats) 184-443, 547-592 -
psp04158 TAF15N(1-155) 1-155 -
psp05113 TAF15-IDR 1-176, 592-592 -
psp00329 TAF15_RBD_181-589 (19Y->S) 184-592 Y418S, Y427S, Y437S, Y446S, Y455S, Y463S, Y471S, Y479S, Y486S, Y494S, Y501S, Y508S, Y515S, Y522S, Y531S, Y541S, Y549S, Y558S, Y566S
psp02481 TAF15_RBD_181-589 (10Y->S) 184-592 Y418S, Y437S, Y455S, Y471S, Y486S, Y501S, Y515S, Y531S, Y549S, Y566S
psp02601 TAF15_PLD_1-180 (D/E->G) 1-59, 63-183 D3G, E13G, D43G, E71G, E93G, D106G, D109G, D114G, D117G, D123G, D130G, E131G, D136G, D140G, E154G, D162G, D163G, D166G, E172G, D173G
psp02966 TAF15_PLD_1-180 (Y->S) 1-60, 64-183 Y7S, Y17S, Y20S, Y28S, Y35S, Y38S, Y46S, Y50S, Y53S, Y56S, Q60S, Y67S, Y70S, Y78S, Y83S, Y105S, Y110S, Y116S, Y122S, Y129S, Y135S, Y142S, Y149S, Y156S, Y170S, Y177S
psp00142 TAF15 IDR-FOXA1 - -
psp02802 TAF15_RBD_(12_repeats) - -

Orthologs and Paralogs

No orthologs or paralogs found for this protein in the database.

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence