HSP48ΔC-term

ID psp01216
Organism Dictyostelium discoideum
Length 145

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
31217303 - Negative

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp04252 HSP48 1-416 - ✓
psp01216 HSP48ΔC-term 1-145 -
psp04227 HSP48ΔN-term 146-416 -

Orthologs and Paralogs

ID Name Organism Length
psp01885 Hsp104 Saccharomyces cerevisiae 908
psp00833 HSPA8 Homo sapiens 646
psp00989 Hsp26 Saccharomyces cerevisiae 214
psp01068 Hsp42 Saccharomyces cerevisiae 375
psp00248 HSPA8 243-283 Homo sapiens 41
psp00954 HSPA8 1-242 Homo sapiens 242
psp01379 HSPA8 1-283 Homo sapiens 283
psp02262 HSPA8 492-646 Homo sapiens 155
psp02434 HSPA8 Δ243-283 Homo sapiens 605
psp03476 HSPA8 1-491 Homo sapiens 491
psp01974 HSPB8 Homo sapiens 196

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence