AKAP95 Δ(101-210)

ID psp01037
Organism Homo sapiens
Length 582

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
32719551 Positive Negative

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp01622 AKAP95 1-692 - ✓
psp01037 AKAP95 Δ(101-210) 1-100, 211-692 -
psp00626 AKAP95 1-100 1-110 -
psp02633 AKAP95 306-692 306-692 -
psp02711 AKAP95 (1-340) 1-340 -
psp03746 AKAP95 101-210 101-210 -
psp04306 AKAP95 211-340 211-340 -
psp04882 AKAP95 1-340 Δ(101-210) 1-100, 211-340 -
psp00180 AKAP95 (101-210 YF) 101-210 Y134F, Y146F, Y150F, Y152F, Y154F, Y170F
psp01862 AKAP95 (101-210 YA) 101-210 Y134A, Y146A, Y150A, Y152A, Y154A, Y170A
psp05200 AKAP95 (101-210 YS) 101-210 Y134S, Y146S, Y150S, Y152S, Y154S, Y170S
psp02463 AKAP95-Lsm4IDR - -
psp02553 AKAP95-Pub1IDR - -
psp04435 AKAP95-hnRNPA1IDR - -

Orthologs and Paralogs

No orthologs or paralogs found for this protein in the database.

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence