PEX14 CC-CTD F229A

ID psp00915
Organism Homo sapiens
Length 239

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
40555785 Positive -

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp01265 PEX14 1-377 -
psp00915 PEX14 CC-CTD F229A 139-377 F229A
psp00671 PEX14 CTD (226-377) 226-377 -
psp04806 PEX14 CC-CTD (139-377) 139-377 -
psp05120 PEX14 CC (139-225) 139-225 -
psp00592 PEX14 CC-CTD-CS1 139-377 R227D, D263R, E298K, R351E, E359R, R365E, E373R
psp01226 PEX14 CC-CTD RKA17 139-377 R226A, R227A, K237A, K246A, K278A, K306A, R310A, K319A, R320A, K323A, R347A, R350A, R351A, K363A, R365A, R366A, R376A
psp01831 PEX14 CC-CTD W241A 139-377 W241A
psp02087 PEX14 CC-CTD WFYA 139-377 F229A, W241A, Y290A
psp02194 PEX14 CC-CTD-CS3 139-377 E279R, R310E, E348R, R376E
psp03041 PEX14 CC-CTD WFA 139-377 F229A, W241A
psp03873 PEX14 CC-CTD EQDN9 139-377 F229A, W241A, Y290A, D325N, E326Q, E327Q, D328N, E329Q, E330Q, D331N, D332N, D333N
psp04449 PEX14 CC-CTD-CS2 139-377 R226E, R227D, K246E, D263R, E298R, E316R, E326R, E329K, E330R, D338R, R350E, R351E, R365E, R366D
psp04860 PEX14 CC-CTD Y290A 139-377 Y290A
psp00201 PEX14 CC-CTD Flag - -
psp03722 PEX14-CC G3BP1 - -
psp04294 PEX14-CC TDP43 - -

Orthologs and Paralogs

ID Name Organism Length
psp04334 PEX14 Arabidopsis thaliana 507

Biophysical Features

The chart can zoom in and zoom out by mouse wheel.

IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence