ANXA11

Synonyms: Annexin A11, Annexin-11, ANX11, 56 kDa autoantigen, ANXA11, Annexin XI, Calcyclin-associated annexin 50, CAP-50

ID psp00748
Organism Homo sapiens
Length 505
Source UniProt: P50995

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
31539493 Positive Positive
32661370 Positive -
33087501 Positive Positive
33597515 Positive -
40118863 Positive Positive

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp00748 ANXA11 1-505 - ✓
psp02307 ANXA11 1-185 1-185 -
psp02613 Annexin A11 2−196 2-196 -
psp03923 ANXA11 186-502 186-502 -
psp00340 ANXA11 H390P - H390P
psp01475 ANXA11 R456H - R456H
psp03254 ANXA11 R235Q - R235Q
psp04669 ANXA11 G38R - G38R
psp04881 ANXA11 D40G - D40G
psp05121 ANXA11 R346C - R346C
psp00551 Annexin A11 2−196 G175R 2-196 G175R
psp01637 Annexin A11 2−196 G189E 2-196 G189E
psp04523 Annexin A11 2−196 D40G 2-196 D40G
psp05197 Annexin A11 2−196 G38R 2-196 G38R

Orthologs and Paralogs

No orthologs or paralogs found for this protein in the database.

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence