nArgBP2

Synonyms: Neural ArgBP2, Arg/Abl-interacting protein 2, Argbp2, ArgBP2, nArgBP2, Sorbs2, Arg-binding protein 2, Sorbin, Sorbin and SH3 domain-containing protein 2

ID psp00585

Organism Rattus norvegicus

Length 1196

Source UniProt: O35413

PS Record in Articles

Reference (Pubmed ID)	In vitro results	In vivo results
36599935	Positive	Positive

Protein Sequence

Sequence Variants

ID	Name	Remain region	Mutation sites	Ref seq
psp00585	nArgBP2	1-1196	-	✓
psp03803	nArgBP2 959-1196	959-1196	-
psp04925	nArgBP2 1-958	1-958	-
psp02384	nArgBP2 959-1196-3S3D	959-1196	S975D, S1119D, S1179D
psp03473	nArgBP2 959-1196-3S3A	959-1196	S975A, S1119A, S1179A

Orthologs and Paralogs

No orthologs or paralogs found for this protein in the database.

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence