SP1 ΔM

ID psp00043
Organism Homo sapiens
Length 520

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
38976739 Negative -

Protein Sequence

Sequence Variants

ID Name Remain region Mutation sites Ref seq
psp05192 SP1 1-785 - ✓
psp00043 SP1 ΔM 1-265, 531-785 -
psp01313 SP1-N 1-269 -
psp01751 SP1-C 515-785 -
psp02413 SP1 ΔC 1-514 -
psp02698 SP1 ΔN 270-785 -
psp04333 SP1-M 266-530 -

Orthologs and Paralogs

ID Name Organism Length
psp04308 Sp1 exon3 Mus musculus 501

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence