SGK3

Synonyms: EC 2.7.11.1, SGK3, Serum/glucocorticoid-regulated kinase-like, SGKL, Serine/threonine-protein kinase Sgk3, CISK, Serum/glucocorticoid-regulated kinase 3, Cytokine-independent survival kinase

ID psp01800
Organism Homo sapiens
Length 496
Source UniProt: Q96BR1

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
33988507 - Positive

Protein Sequence

Sequence Variants

No protein variants available for this protein.

Orthologs and Paralogs

ID Name Organism Length
psp04666 SGS3 Arabidopsis thaliana 625
psp01321 SGS3ΔPrLD Arabidopsis thaliana 432
psp01599 SGS3dCC (1-420) Arabidopsis thaliana 420
psp02640 SGS3dXS (1-290+420-625) Arabidopsis thaliana 496
psp03472 SGS3dN (220-625) Arabidopsis thaliana 406

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence