AR V7

ID psp01449
Organism Synthetic
Length 644

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
36229685 - Positive

Protein Sequence

Sequence Variants

No protein variants available for this protein.

Orthologs and Paralogs

ID Name Organism Length
psp02343 AR Homo sapiens 920
psp01466 AR-NTD (1-559) 12Q Homo sapiens 548
psp01749 AR-NTD (1-559) 31Q Homo sapiens 567
psp01837 AR-NTD (1-559) 49Q Homo sapiens 585
psp04485 AR-NTD (1-559) 20Q Homo sapiens 556
psp02606 AR A574D Homo sapiens 920
psp01486 AR LBD (669-919) Homo sapiens 251
psp01621 AR DBD-hinge-LDB (556-920) Homo sapiens 365
psp01818 AR NTD (1-555) Homo sapiens 555
psp02811 AR NTD-DBD (1-634) Homo sapiens 634
psp03185 AR ΔPolyQ (58-91) Homo sapiens 886
psp04273 AR Hinge-LBD (629-920) Homo sapiens 292
psp04292 AR ΔAF1 (144-450) Homo sapiens 613
psp04615 AR Δ425-496 Homo sapiens 848
psp04690 AR DBD (556-634) Homo sapiens 79
psp04966 AR ΔFXXLF (23-27) Homo sapiens 915

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence