Galectin-1

Synonyms: HBL, HPL, S-Lac lectin 1, HLBP14, Lactose-binding lectin 1, Putative MAPK-activating protein PM12, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, Gal-1, Galaptin, LGALS1, Lectin galactoside-binding soluble 1, Galectin-1, 14 kDa laminin-binding protein

ID psp00161
Organism Homo sapiens
Length 135
Source UniProt: P09382

PS Record in Articles

Reference (Pubmed ID) In vitro results In vivo results
33952698 Negative -

Protein Sequence

Sequence Variants

No protein variants available for this protein.

Orthologs and Paralogs

ID Name Organism Length
psp02950 Galectin-2 Homo sapiens 132
psp05153 Gal3 Homo sapiens 250
psp00964 Galectin-3 NTD Homo sapiens 109
psp02225 galectin-3 NTD Homo sapiens 112
psp01990 Galectin-3 NTD-D3/9G Homo sapiens 109
psp04236 Galectin-3 NTD-D9G Homo sapiens 109
psp05064 Galectin-3 NTD-D3G Homo sapiens 109
psp01019 His-Galectin-3 13-250 Homo sapiens 244
psp01812 His-Galectin-3 111-250 Homo sapiens 146
psp03088 His-Galectin-3 69-250 Homo sapiens 188
psp04528 His-Galectin-3 Homo sapiens 256
psp04998 His-Galectin-3 1-108 Homo sapiens 114

Biophysical Features

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IDR (Intrinsically Disordered Region) was predicted by Mobidb-lite 4.0, please refer to: MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness.

Pi-Pi interaction was predicted by PScore, please refer to: Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PLAAC and PrD. like were both predicted by PLAAC, please refer to: PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.

LCR (Low Complexity Region) was predicted by SEG, please refer to: Statistics of local complexity in amino acid sequences and sequence databases.

NCPR (Net Charge Per Residue), FCR (Fraction of Charged Residues) and hydrophobicity were both computated by CIDER, please refer to: CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Polarity was computated by ProtScale, please refer to: ProtScale.

SASA (Solvent-Accessible Surface Area) was computated by BioPython based on the predicted structure, please refer to: Bio.PDB.SASA module.

Protein Structure

Colered by pLDDT:
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

Protein structure was predicted by Chai-1, which also produces predicted local distance difference test (pLDDT) score between 0 and 100.

For pLDDT, please refer to: pLDDT: Understanding local confidence